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Smart implants and implantable biosensors

Another aspect of my research involves the development of smart implants that contain embedded passive microsensors to monitor dynamic tissue reconstruction and in situ bone formation. Monitoring bone healing at the titanium implant-tissue biointerface in vivo is crucial for determining the integration and stability of endosseous implants. We have already developed and evaluated a titanium dioxide-coated implantable biosensor for minimal-invasive and continuous monitoring of implant stability. Based on initial animal studies, we aim in future to implement a state-of-the-art wireless, passive sensing strategy in combination with custom electronics and readout (e.g. fully integrated PCB) to remotely operate the smart implant.